T4 RNA Ligase 1

T4 RNA Ligase 1 catalyses the formation of a phosphodiester bond between the terminal 5′ phosphate and 3′ hydroxyl groups of single-stranded RNA or DNA. It requires ATP as a cofactor.

One unit is defined as the amount of enzyme required to ligate 50% of an equimolar mix (125nM) of a single-stranded 5′ FAM-labeled 17-mer RNA to a 5′ phosphorylated 18-mer RNA in 20 µL at 37°C for 30 minutes.

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Cat No.	Product	Price	Quantity
TRL101	Kit 12,000U T4 RNA ligase 1 (20U/uL; 100uL), 10X buffer	£144
TRL102	Kit 210,000U T4 RNA ligase 1 (20U/uL; 500uL), 10X buffer	£334

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Inspiralis

Inspiralis在提供高质量拓扑异构酶，连接酶和解旋酶方面享誉全球，包括检测试剂盒，底物和筛选服务。

We are located in laboratories adjacent to the academic research centres of the John Innes Centre and the University of East Anglia on the Norwich Research Park. We maintain close links with the academic research group of Professor Maxwell, helping us to remain at the forefront of the topoisomerase field. The experience of our staff and the connections with the academic group allow us to provide a high level of support to ensure that researchers are able to get the best results using our products. The same scientists who produce our enzymes and substrates also provide the technical support.

Our aim is to provide pharmaceutical companies, and others involved in drug development, with the necessary tools to develop and screen novel anti-infective and anti-cancer compounds. In order to achieve this we will continue to expand the range of topoisomerase products and screening services we offer.

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